Ooooh Very Cool!

The beautiful chaos of watching 12 frantic astrophysics students try to save a theoretical astronaut from falling into a black hole. I’ve never seen a group of people work so quickly and efficiently before.

Morning on Mars

6 Martian sunrises, as seen by the HiRISE orbiter.  Once again, not artist’s renditions.

Save Science

Not sure what to say. I’m actually legitimately nervous the Cheeto-in-Chief will demand a hold on the National Science Foundation grants like he did the EPA (disclaimer, the NSF is where my job comes from).

I feel so terrible for all the scientists and students who are now out of the job 

Why Sequencing DNA in Space is a Big Deal

… And How You Can Talk to the Scientists Who Made It Happen

Less than one month ago, DNA had never been sequenced in space. As of today, more than one billion base pairs of DNA have been sequenced aboard the International Space Station, Earth’s only orbiting laboratory. The ability to sequence the DNA of living organisms in space opens a whole new world of scientific and medical possibilities. Scientists consider it a game changer. 

NASA astronaut Kate Rubins, who has a background in genomics, conducted the sequencing on the space station as part of the Biomolecule Sequencer investigation. A small, commercial, off-the-shelf device called MinION (min-EYE-ON), manufactured by Oxford Nanopore Technologies in the UK, was used to sequence the DNA of bacteria, a virus and rodents. Human DNA was not sequenced, and there are no immediate plans to sequence human DNA in space. 

(Image Credit: Oxford Nanopore Technologies)

The MinION is about the size of a candy bar, and plugs into a laptop or tablet via USB connection, which also provides power to the device. The tiny, plug and play sequencer is diminutive compared to the large microwave-sized sequencers used on Earth, and uses much less power. Unlike other terrestrial instruments whose sequencing run times can take days, this device’s data is available in near real time; analysis can begin within 10-15 minutes from the application of the sample.

Having real-time analysis capabilities aboard the space station could allow crews to identify microbes, diagnose infectious disease and collect genomic and genetic data concerning crew health, without having to wait long periods of time to return samples to Earth and await ground-based analysis.

The first DNA sequencing was conducted on Aug. 26, and on Sept. 14, Rubins and the team of scientists back at NASA’s Johnson Space Center in Houston hit the one-billionth-base-pairs-of-DNA-sequenced mark.

Have more questions about how the Biomolecule Sequencer works, or how it could benefit Earth or further space exploration? Ask the team of scientists behind the investigation, who will be  available for questions during a Reddit Ask Me Anything on /r/science on Wednesday, Sept. 29 at 2 p.m. EDT. 

The participants are:

Dr. Aaron Burton, NASA Johnson Space Center, Planetary Scientist and Principal Investigator

Dr. Sarah Castro-Wallace, NASA Johnson Space Center, Microbiologist and Project Manager

Dr. David J. Smith, NASA Ames Research Center, Microbiologist

Dr. Mark Lupisella, NASA Goddard Space Flight Center, Systems Engineer

Dr. Jason P. Dworkin, NASA Goddard Space Flight Center, Astrobiologist

Dr. Christopher E. Mason, Weill Cornell Medicine Dept. of Physiology and Biophysics, Associate Professor

2017 Perseids Meteor Shower Peaks This Weekend

Despite a bright moon, stargazers might see celestial fireworks Saturday night

That’s tonight fyi

Living and Working Aboard Station

 Join us on Facebook Live for a conversation with astronaut Kate Rubins and the director of the National Institutes for Health on Tuesday, October 18 at 11:15 a.m. ET.

Astronaut Kate Rubins has conducted out of this world research aboard Earth’s only orbiting laboratory. During her time aboard the International Space Station, she became the first person to sequence DNA in space. On Tuesday, she’ll be live on Facebook with National Institute of Health director Francis Collins, who led the effort to map the human genome. You can submit questions for Kate using the hashtag #SpaceChat on Twitter, or during the live event. Here’s a primer on the science this PhD astronaut has been conducting to help inspire your questions: 

Kate has a background in genomics (a branch of molecular genetics that deals with the study of genomes,specifically the identification and sequencing of their constituent genes and the application of this knowledge in medicine, pharmacy,agriculture, and other fields). When she began her tenure on the station, zero base pairs of DNA had been sequenced in space. Within just a few weeks, she and the Biomolecule Sequencer team had sequenced their one billionth base of DNA aboard the orbital platform.

“I [have a] genomics background, [so] I get really excited about that kind of stuff,” Rubins said in a downlink shortly after reaching the one billion base pairs sequenced goal.

Learn more about this achievement:

+First DNA Sequencing in Space a Game Changer

+Science in Short: One Billion Base Pairs Sequenced

Why is DNA Sequencing in Space a Big Deal?

A space-based DNA sequencer could identify microbes, diagnose diseases and understand crew member health, and potentially help detect DNA-based life elsewhere in the solar system.

+Why Sequencing DNA in Space is a Big Deal

https://youtu.be/1N0qm8HcFRI 

Miss the Reddit AMA on the subject? Here’s a transcript:

+NASA AMA: We just sequenced DNA in space for the first time. Ask us anything! 

NASA and Its Partnerships

We’re not doing this alone. Just like the DNA sequencing was a collaborative project with industry, so is the Eli Lilly Hard to Wet Surfaces investigation. In this experiment aboard the station, astronauts will study how certain materials used in the pharmaceutical industry dissolve in water while in microgravity. Results from this investigation could help improve the design of tablets that dissolve in the body to deliver drugs, thereby improving drug design for medicines used in space and on Earth. Learn more about what we and our partners are doing:

+Eli Lilly Hard to Wet Surfaces – been happening the last week and a half or so

Researchers to Test How Solids Dissolve in Space to Design Better Tablets and Pills on Earth

With our colleagues at the Stanford University School of Medicine, we’re also investigating the effects of spaceflight on stem cell-derived heart cells, specifically how heart muscle tissue, contracts, grows and changes  in microgravity and how those changes vary between subjects. Understanding how heart muscle cells change in space improves efforts for studying disease, screening drugs and conducting cell replacement therapy for future space missions. Learn more:

+Heart Cells

+Weekly Recap From the Expedition Lead Scientist for Aug. 18, 2016 

It’s Not Just Medicine

Kate and her crew mates have also worked on the combustion experiments.

Kate has also worked on the Bigelow Expandable Activity Module (BEAM), an experimental expandable capsule that docks with the station. As we work on our Journey to Mars, future space habitats  are a necessity. BEAM, designed for Mars or other destinations, is a lightweight and relatively simple to construct solution. Kate has recently examined BEAM, currently attached to the station, to take measurements and install sensors.

Kate recently performed a harvest of the Plant RNA Regulation experiment, by removing seed cassettes and stowing them in cold stowage.

The Plant RNA Regulation investigation studies the first steps of gene expression involved in development of roots and shoots. Scientists expect to find new molecules that play a role in how plants adapt and respond to the microgravity environment of space, which provides new insight into growing plants for food and oxygen supplies on long-duration missions. Read more about the experiment:

+Plant RNA Harvest

NASA Astronaut Kate Rubins is participating in several investigations examining changes in her body as a result of living in space. Some of these changes are similar to issues experienced by our elderly on Earth; for example, bone loss (osteoporosis), cardiovascular deconditioning, immune dysfunction, and muscle atrophy. Understanding these changes and how to prevent them in astronauts off the Earth may help improve health for all of us on the Earth. In additional, the crew aboard station is also working on more generalized studies of aging.

+ Study of the effects of aging on C. elegans, a model organism for a range of biological studies.

Unfollow me if you wish, but this blog will NEVER support Trump and instead supports the LGBT community, racial minorities, women, people with disabilities, immigrants, Muslims, Jewish people, and anyone else who is afraid now. I am with you, and this will always be a safe space for you.

The Body’s Price on Space Exploration

It can be easy to get wrapped up in the dollar amount when talking about the price of sending humans to Mars but there is a factor that no amount of government or private funding can overcome: the human body.

Read more on Miss Aerospace

Scientists find another sign suggesting life existed on Mars

According to new research published in the Journal of Geophysical Research, scientists are getting even more indicators that life once existed on Mars. The latest proof? Carbonates found in 3.8 billion-year-old rock in the Huygens basin.

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